1H MR Spectroscopy* of the Breast at 1.5T and at 3T
Nouha Salibi, Ph.D.1, Marianne Vorbuchner2, Jan Ruff, Ph.D.2
1Siemens Medical Solutions, Malvern, USA. 2Siemens Medical Solutions, MREA, Erlangen, Germany | 2007-05-30
Breast 1H MRS: Monitoring response to chemotherapy
Figures 5 and 6 illustrate the use of MR spectroscopy in monitoring the effect of chemotherapy on a diagnosed invasive breast carcinoma†. Spectra were acquired following each of the 6 cycle treatment. They demonstrate a gradual reduction in the choline peak, which is hardly visible after the sixth cycle of chemotherapy. Using the Phoenix functionality of the syngo software the same measurement protocol was recalled for each follow-up examination. This insured that the same parameters were used for all measurements except for the voxel size, which was adjusted to the reduced size of the tumor.
† Courtesy of Professor T. J. Vogl, University of Frankfurt/Main, Germany.
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